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Upper Airway (Hypoglossal Nerve) Stimulation for Treatment of Obstructive Sleep Apnea

  • Rishi Jay Gupta
    Affiliations
    Oral and Maxillofacial Surgery Section, Department of Dental Service, San Francisco VA Health Care System, 4150 Clement Street (160), San Francisco, CA 94121, USA

    Department of Oral and Maxillofacial Surgery, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 94143, USA

    Department of Otolaryngology Head and Neck Surgery, University of California, Davis, 2521 Stockton Blvd, Sacramento, CA 95817, USA
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  • Deepak Kademani
    Affiliations
    Head and Neck Oncologic and Reconstructive Surgery, Department of Oral and Maxillofacial Surgery, North Memorial Medical Center, Minneapolis, MN 55422, USA
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  • Stanley Yung-Chuan Liu
    Correspondence
    Corresponding author.
    Affiliations
    Division of Sleep Surgery, Department of Otolaryngology, Stanford Sleep Surgery Fellowship, Stanford University School of Medicine, 801 Welch Road, Stanford, CA 94305, USA
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      Obstructive sleep apnea is a multilevel process consisting of physiologic and anatomic obstructive patterns leading to partial or complete collapse of the upper airway and resulting comorbidities.

      Keywords

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      References

        • Dempsey J.A.
        • Veasey S.C.
        • Morgan B.J.
        • et al.
        Pathophysiology of sleep apnea.
        Physiol Rev. 2010; 90: 47-112
        • Young T.
        • Finn L.
        • Peppard P.E.
        • et al.
        Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort.
        Sleep. 2008; 31: 1071-1078
        • Wolk R.
        • Somers V.K.
        Sleep and the metabolic syndrome.
        Exp Physiol. 2007; 92: 67-78
        • Einhorn D.
        • Stewart D.A.
        • Erman M.K.
        • et al.
        Prevalence of sleep apnea in a population of adults with type 2 diabetes mellitus.
        Endocr Pract. 2007; 13: 355-362
        • Caples S.M.
        • Rowley J.A.
        • Prinsell J.R.
        • et al.
        Surgical modifications of the upper airway for obstructive sleep apnea in adults: a systematic review and meta-analysis.
        Sleep. 2010; 33: 1396-1407
        • Holty J.E.
        • Guilleminault C.
        Maxillomandibular advancement for the treatment of obstructive sleep apnea: a systematic review and meta-analysis.
        Sleep Med Rev. 2010; 14: 287-297
        • Friedman M.
        • Jacobowitz O.
        • Hwang M.S.
        • et al.
        Targeted hypoglossal nerve stimulation for the treatment of obstructive sleep apnea: six-month results.
        Laryngoscope. 2016; 126: 2618-2623
        • Mwenge G.B.
        • Rombaux P.
        • Lengele B.
        • et al.
        Hypoglossal nerve stimulation for obstructive sleep apnea.
        Prog Neurol Surg. 2015; 29: 94-105
        • Van de Heyning P.H.
        • Badr M.S.
        • Baskin J.Z.
        • et al.
        Implanted upper airway stimulation device for obstructive sleep apnea.
        Laryngoscope. 2012; 122: 1626-1633
        • Schwartz A.R.
        • Bennett M.L.
        • Smith P.L.
        • et al.
        Therapeutic electrical stimulation of the hypoglossal nerve in obstructive sleep apnea.
        Arch Otolaryngol Head Neck Surg. 2001; 127: 1216-1223
        • Goding G.S.
        • Tesfayesus W.
        • Kezirian E.J.
        Hypoglossal nerve stimulation and airway changes under fluoroscopy.
        Otolaryngol Head Neck Surg. 2012; 146: 1017-1022
        • Safiruddin F.
        • Vanderveken O.M.
        • de Vries N.
        • et al.
        Effect of upper-airway stimulation for obstructive sleep apnoea on airway dimensions.
        Eur Respir J. 2015; 45: 129-138
        • Vanderveken O.M.
        • Maurer J.T.
        • Hohenhorst W.
        • et al.
        Evaluation of drug-induced sleep endoscopy as a patient selection tool for implanted upper airway stimulation for obstructive sleep apnea.
        J Clin Sleep Med. 2013; 9: 433-438
        • Kezirian E.J.
        • Hohenhorst W.
        • de Vries N.
        Drug-induced sleep endoscopy: the VOTE classification.
        Eur Arch Otorhinolaryngol. 2011; 268: 1233-1236
        • Strohl K.P.
        • Baskin J.
        • Lance C.
        • et al.
        Origins of and implementation concepts for upper airway stimulation therapy for obstructive sleep apnea.
        Respir Investig. 2016; 54: 241-249
        • Woodson B.T.
        • Strohl K.P.
        • Soose R.J.
        • et al.
        Upper airway stimulation for obstructive sleep apnea: 5-year outcomes.
        Otolaryngol Head Neck Surg. 2018; 159: 194-202
        • Yegïn Y.
        • Çelik M.
        • Kaya K.H.
        • et al.
        Comparison of drug-induced sleep endoscopy and Müller's maneuver in diagnosing obstructive sleep apnea using the VOTE classification system.
        Braz J Otorhinolaryngol. 2017; 83: 445-450
        • Huntley C.
        • Kaffenberger T.
        • Doghramji K.
        • et al.
        Upper airway stimulation for treatment of obstructive sleep apnea: an evaluation and comparison of outcomes at two academic centers.
        J Clin Sleep Med. 2017; 13: 1075-1079
        • Hofauer B.
        • Steffen A.
        • Knopf A.
        • et al.
        Patient experience with upper airway stimulation in the treatment of obstructive sleep apnea.
        Sleep Breath. 2018; ([Epub ahead of print])
        • Boon M.
        • Huntley C.
        • Steffen A.
        • et al.
        Upper airway stimulation for obstructive sleep apnea: results from the ADHERE registry.
        Otolaryngol Head Neck Surg. 2018; 159: 379-385
        • Pietzsch J.B.
        • Liu S.
        • Garner A.M.
        • et al.
        Long-term cost-effectiveness of upper airway stimulation for the treatment of obstructive sleep apnea: a model-based projection based on the STAR trial.
        Sleep. 2015; 38: 735-744
        • Knauert M.
        • Naik S.
        • Gillespie M.B.
        • et al.
        Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome.
        World J Otorhinolaryngol Head Neck Surg. 2015; 1: 17-27
        • Shah J.
        • Russell J.O.
        • Waters T.
        • et al.
        Uvulopalatopharyngoplasty vs CN XII stimulation for treatment of obstructive sleep apnea: a single institution experience.
        Am J Otolaryngol. 2018; 39: 266-270
        • Huntley C.
        • Chou D.
        • Doghramji K.
        • et al.
        Preoperative drug induced sleep endoscopy improves the surgical approach to treatment of obstructive sleep apnea.
        Ann Otol Rhinol Laryngol. 2017; 126: 478-482
        • Liu S.Y.
        • Huon L.K.
        • Iwasaki T.
        • et al.
        Efficacy of maxillomandibular advancement examined with drug-induced sleep endoscopy and computational fluid dynamics airflow modeling.
        Otolaryngol Head Neck Surg. 2016; 154: 189-195
        • Liu S.Y.
        • Riley R.W.
        Continuing the original Stanford sleep surgery protocol from upper airway reconstruction to upper airway stimulation: our first successful case.
        J Oral Maxillofac Surg. 2017; 75: 1514-1518