Advertisement

Autologous Fat Transfer for Maxillofacial Reconstruction

  • Ryan M. Diepenbrock
    Correspondence
    Corresponding author. Diepenbrock Facial Cosmetic Surgery, 171 Butcher Road, Suite A, Vacaville, CA 95687.
    Affiliations
    Oral and Maxillofacial Surgery, David Grant USAF Medical Center, 101 Bodin Cir, Travis AFB, CA 94535, USA

    Diepenbrock Facial Cosmetic Surgery, 171 Butcher Road, Suite A, Vacaville, CA 95687, USA
    Search for articles by this author
  • J. Marshall Green III
    Affiliations
    Oral and Maxillofacial Surgery, Naval Medical Center Portsmouth, 620 John Paul Jone Cir, Portsmouth, VA 23708, USA

    Coastal Facial Aesthetic Surgery, 5408 Discovery Park Boulevard #101, Williamsburg, VA 23118, USA
    Search for articles by this author
Published:December 07, 2017DOI:https://doi.org/10.1016/j.cxom.2017.11.002
      Fat transfer (grafting) is an essential part of today’s maxillofacial reconstructive treatment algorithm. Autologous fat is a versatile graft essential for soft tissue reconstruction.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      References

        • Neuber G.A.
        Fet transplantation.
        Chir Kongr Verhandl Dtsch Gesellsch Chir. 1893; 22: 66-68
      1. Bagheri SC, Bell RB, Khan HA, editors. Current therapy in oral and maxillofacial surgery. Philadelphia: Saunders; 2012.

        • Coleman S.
        Structural fat grafting: more than a permanent filler.
        Plast Reconstr Surg. 2006; 118: 108-120
        • Bucky L.P.
        • Kanchwala S.K.
        The role of autogenous fat and alternative fillers in the aging face.
        Plast Reconstr Surg. 2007; 120: 89S-97S
        • Tholpady S.
        • Llull R.
        • Ogle R.
        • et al.
        Adipose tissue: stem cells and beyond.
        Clin Plast Surg. 2006; 33: 55-62
        • Fruhbeck G.
        Overview of adipose tissue and its role in obesity and metabolic disorders.
        Methods Mol Biol. 2008; 456: 1-22
        • Von Heimburg D.
        • Hemmrich K.
        • Haydarlioglu S.
        • et al.
        Comparison of viable cell yield from excised versus aspirated adipose tissue.
        Cells Tissues Organs. 2004; 178: 87
        • Smahel J.
        Experimental implantation of adipose tissue fragments.
        Br J Plast Surg. 1989; 42: 207
        • Wolter T.P.
        • Von Heimburg D.
        • Stoffels I.
        • et al.
        Cryopreservation of mature human adipocytes: in vitro measurement of viability.
        Ann Plast Surg. 2005; 55: 408
        • Halberg N.
        • Wernstedt-Asterholm I.
        • Scherer P.E.
        The adipocyte as an endocrine cell.
        Endocrinol Metab Clin North Am. 2008; 37: 753Y768
        • Cao Y.
        Angiogenesis modulates adipogenesis and obesity.
        J Clin Invest. 2007; 117: 2362-2368
        • Zuk P.A.
        • Zhu M.
        • Mizuno H.
        • et al.
        Multilineage cells from human adipose tissue: implications for cell-based therapies.
        Tissue Eng. 2001; 7: 211-228
        • Pallua N.
        • Pulsfort A.K.
        • Suschek C.
        • et al.
        Content of the growth factors bFGF, IGF-1, VEGF, and PDGF-BB in freshly harvested lipoaspirate after centrifugation and incubation.
        Plast Reconstr Surg. 2009; 123: 826-833
        • Rehman J.
        • Traktuev D.
        • Li J.
        • et al.
        Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells.
        Circulation. 2004; 109: 1292
        • Rigotti G.
        • Marchi A.
        • Galie M.
        • et al.
        Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells.
        Plast Reconstr Surg. 2007; 119 ([discussion: 1423–4]): 1409-1422
        • Aust L.
        • Devlin B.
        • Foster S.J.
        • et al.
        Yield of human adipose-derived adult stem cells from liposuction aspirates.
        Cytotherapy. 2004; 6: 7
        • Thanik V.D.
        • Chang C.C.
        • Lerman O.Z.
        • et al.
        Murine model for studying diffusely injected human fat.
        Plast Reconstr Surg. 2009; 124: 74Y81
        • Strem B.M.
        • Hicok K.C.
        • Zhu M.
        • et al.
        Multipotential differentiation of adipose tissue-derived stem cells.
        Keio J Med. 2005; 54: 132
        • Zuk P.A.
        • Zhu M.
        • Ashjian P.
        • et al.
        Human adipose tissue is a source of multipotent stem cells.
        Mol Biol Cell. 2002; 13: 4279-4295
        • Phulpin B.
        • Gangloff P.
        • Tran N.
        • et al.
        Rehabilitation of irradiated head and neck tissues by autogenous fat transplantation.
        Plast Reconstr Surg. 2009; 123: 1187-1197
        • Sultan S.
        • Stern C.
        • Allen R.
        • et al.
        Human fat grafting alleviates radiation skin damage in a murine model.
        Plast Reconstr Surg. 2011; 128: 363-372
        • Lendeckel S.
        • Jödicke A.
        • Christophis P.
        • et al.
        Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report.
        J Craniomaxillofac Surg. 2004; 32: 370-373
        • Taylor J.A.
        Bilateral orbitozygomatic reconstruction with tissue-engineered bone.
        J Craniofac Surg. 2010; 21: 1612-1614
        • Franchi G.
        • Nadlub N.
        • Diner P.A.
        • et al.
        Orbital soft tissue surgery for patients with Treacher-Collins or Nager syndrome. A new surgical approach with early correction of soft tissue: prospective study.
        Br J Oral Maxillofac Surg. 2015; 53: 421-425
        • Agostini T.
        • Spinelli G.
        • Marino G.
        • et al.
        Esthetic restoration in progressive hemifacial atrophy (Romberg disease): structural fat grafting versus local/free flaps.
        J Craniofac Surg. 2014; 25: 783-787
        • Shuck J.
        • Iorio M.
        • Hung R.
        • et al.
        Autologous fat grafting and injectable dermal fillers for human immunodeficiency virus-associated facial lipodystrophy: a comparison of safety, efficacy, and long-term treatment outcomes.
        Plast Reconstr Surg. 2013; 131: 499-506
        • Teplica D.
        Discussion: autologous fat grafting and injectable dermal fillers for human immunodeficiency virus-associated facial lipodystrophy: a comparison of safety, efficacy, and long-term treatment outcomes.
        Plast Reconstr Surg. 2013; 131: 507-509