There are a variety of nonsurgical cancer treatment modalities, such as chemotherapy,
radiotherapy, hematopoietic stem cell transplantation, and targeted therapy.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Atlas of the Oral and Maxillofacial Surgery Clinics of North AmericaAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Oral complications of targeted cancer therapies: a narrative literature review.Oral Oncol. 2011; 47: 441-448
- Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma.Cancer. 2006; 106: 329-336
- Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: literature review and consensus statements.Crit Rev Oncol Hematol. 2016; 100: 147-166
- Oral mucositis in head and neck cancer: risk, biology, and management.Am Soc Clin Oncol Educ book. 2013; : e236-e240
- The burdens of cancer therapy. Clinical and economic outcomes of chemotherapy-induced mucositis.Cancer. 2003; 98: 1531-1539
- MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.Cancer. 2014; 120: 1453-1461
- Chronic oral mucositis after radiotherapy to the head and neck: a new insight.Support Care Cancer. 2016; 24: 4825-4830
- Neutropenic ulceration. A distinctive clinical entity.J Periodontol. 1987; 58: 51-55
- A case of chronic severe neutropenia: oral findings and consequences of short-term granulocyte colony-stimulating factor treatment.Aust Dent J. 1998; 43: 9-13
- Oral pyogenic granuloma after bone marrow transplant in the pediatric/adolescent population: report of 5 cases.J Pediatr Hematol Oncol. 2016; 38: 570-573
- Pyogenic granuloma of the tongue early after allogeneic bone marrow transplantation for multiple myeloma.Leuk Lymphoma. 2000; 37: 445-449
- Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib.Br J Dermatol. 2009; 161: 1045-1051
- A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients.Oral Oncol. 2013; 49: 293-298
- Oral mucosal injury caused by mammalian target of rapamycin inhibitors: emerging perspectives on pathobiology and impact on clinical practice.Cancer Med. 2016; 5: 1897-1907
- Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients.Cancer. 2010; 116: 210-215
- Pigmented lesions of the oral mucosa and perioral tissues: a flow-chart for the diagnosis and some recommendations for the management.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008; 105: 606-616
- Oral melanosis after tyrosine kinase inhibition with Imatinib for chronic myelogenous leukemia: report of a case and review of the literature.Dermatol Online J. 2011; 17: 4
- Imatinib-associated hyperpigmentation of the palate in post-HSCT patient.J Craniomaxillofac Surg. 2012; 40: e140-e143
- A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life.Support Care Cancer. 2010; 18: 1039-1060
- Chemotherapy-associated oral sequelae in patients with cancers outside the head and neck region.J Pain Symptom Manage. 2014; 48: 1060-1069
- A longitudinal follow-up of salivary secretion in bone marrow transplant patients.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995; 79: 164-169
- Immediate toxicity during fractionated total body irradiation as conditioning for bone marrow transplantation.Radiother Oncol. 2000; 54: 157-162
- A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact.Support Care Cancer. 2010; 18: 1061-1079
- AAOM Clinical Practice Statement: subject: clinical management of cancer therapy-induced salivary gland hypofunction and xerostomia.Oral Surg Oral Med Oral Pathol Oral Radiol. 2016; 122: 310-312
- Superficial oral mucoceles in cancer patient after radiation therapy: an overlooked yet imperative phenomenon.Oral Oncol. 2016; 52: e1-e2
- Osteoradionecrosis and intensity modulated radiation therapy: an overview.Crit Rev Oncol Hematol. 2016; 107: 39-43
- Osteoradionecrosis in cancer patients: the evidence base for treatment-dependent frequency, current management strategies, and future studies.Support Care Cancer. 2010; 18: 1089-1098
- Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: dental pathologies and osteoradionecrosis (Part 1) literature review and consensus statement.Crit Rev Oncol Hematol. 2016; 97: 131-142
- New perspectives on the conservative management of osteoradionecrosis of the mandible: a literature review.Head Neck. 2016; 38: 1708-1716
- Osteonecrosis of the jaws induced by drugs other than bisphosphonates - a call to update terminology in light of new data.Oral Oncol. 2010; 46: e1
- American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw–2014 update.J Oral Maxillofac Surg. 2014; 72: 1938-1956
- Bisphosphonate-related osteonecrosis of the jaws: a single-center study of 101 patients.J Oral Maxillofac Surg. 2009; 67: 850-855
- Osteonecrosis of the jaw induced by orally administered bisphosphonates: incidence, clinical features, predisposing factors and treatment outcome.Osteoporos Int. 2007; 18: 1363-1370
- Barriers to winning the battle with head-and-neck cancer.Int J Radiat Oncol Biol Phys. 2002; 53: 4-5
- Swallowing dysfunction in head and neck cancer patients treated by radiotherapy: review and recommendations of the supportive task group of the Italian Association of Radiation Oncology.Cancer Treat Rev. 2012; 38: 1033-1049
- Voice and speech outcomes of chemoradiation for advanced head and neck cancer: a systematic review.Eur Arch Otorhinolaryngol. 2010; 267: 1495-1505
- Effectiveness of voice rehabilitation on vocalisation in postlaryngectomy patients: a systematic review.Int J Evid Based Healthc. 2010; 8: 256-258
- Restricted mouth opening in chronic graft-versus-host disease.Oral Surg Oral Med Oral Pathol Oral Radiol. 2016; 121: 201-202
- Supportive and palliative care in dentistry and oral medicine.in: Smith H.S. Pilitsis J.G. The art and science of palliative medicine. AME Publishing Company, Hong Kong (China)2014: 385-405
- A systematic review of dysgeusia induced by cancer therapies.Support Care Cancer. 2010; 18: 1081-1087
- Understanding the impact of taste changes in oncology care.Support Care Cancer. 2016; 24: 1917-1931
- Oral adverse events in cancer patients treated with VEGFR-directed multitargeted tyrosine kinase inhibitors.Oral Oncol. 2015; 51: 1026-1033
- Long-term oral complications of allogeneic haematopoietic SCT.Bone Marrow Transplant. 2012; 47: 265-270
- Cytotoxic chemotherapy-induced odontalgia: a differential diagnosis for dental pain.J Endod. 2010; 36: 1588-1592
- Dental demineralization and caries in patients with head and neck cancer.Oral Oncol. 2015; 51: 824-831
- A systematic review of dental disease in patients undergoing cancer therapy.Support Care Cancer. 2010; 18: 1007-1021
- Extensive dental caries in patients with oral chronic graft-versus-host disease.Biol Blood Marrow Transplant. 2012; 18: 1573-1579
- An apparent unusual relationship between rampant caries and the oral mucosal manifestations of chronic graft-versus-host disease.Oral Surg Oral Med Oral Pathol. 1994; 78: 267-272
- Long-term clinical observation of dental caries in salivary hypofunction patients using a supersaturated calcium-phosphate remineralizing rinse.J Clin Dent. 2009; 20: 87-92
- Anti-caries effect of CPP-ACP in irradiated nasopharyngeal carcinoma patients.Clin Oral Investig. 2015; 19: 1005-1011
- Pulp obliteration in a patient with sclerodermatous chronic graft-versus-host disease.J Endod. 2016; 42: 678-680
- Periodontal disease and periodontal management in patients with cancer.Oral Oncol. 2001; 37: 613-619
- Colonization of the oropharynx with pathogenic microorganisms–a potential risk factor for infection in compromised patients.Chemioterapia : Int J Mediterr Soc Chemother. 1985; 4: 186-191
- Chemotherapy-associated oral infections in adults with solid tumors.Oral Surg Oral Med Oral Pathol. 1983; 55: 113-120
- Infection and mucosal injury in cancer treatment.J Natl Cancer Inst Monographs. 2001; : 31-36
- A systematic review of oral fungal infections in patients receiving cancer therapy.Support Care Cancer. 2010; 18: 985-992
- A systematic review of viral infections associated with oral involvement in cancer patients: a spotlight on Herpesviridea.Support Care Cancer. 2010; 18: 993-1006
- A systematic review of oral herpetic viral infections in cancer patients: commonly used outcome measures and interventions.Support Care Cancer. 2016; 25: 687-700
- Post-transplant lymphoproliferative disorders.Cancer Treat Res. 2015; 165: 305-327
- Oral posttransplantation lymphoproliferative disorder: an uncommon site for an uncommon disorder.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008; 105: 59-64
- Solid cancers after bone marrow transplantation.N Engl J Med. 1997; 336: 897-904
- Impact of chronic GVHD therapy on the development of squamous-cell cancers after hematopoietic stem-cell transplantation: an international case-control study.Blood. 2005; 105: 3802-3811
- Oral epithelial dysplasia and squamous cell carcinoma following allogeneic hematopoietic stem cell transplantation: clinical presentation and treatment outcomes.Bone Marrow Transplant. 2011; 46: 884-891
- Postradiation sarcoma from a free flap.J Craniofac Surg. 2013; 24: 2160-2162
- Postradiation sarcoma of head and neck: report of two cases.Tumori. 1996; 82: 270-272
- Oral and dental late effects in survivors of childhood cancer: a Children's Oncology Group report.Support Care Cancer. 2014; 22: 2009-2019
- Long-term adverse effects of hematopoietic stem cell transplantation on dental development in children.Support Care Cancer. 2009; 17: 1169-1175
- A systematic review of trismus induced by cancer therapies in head and neck cancer patients.Support Care Cancer. 2010; 18: 1033-1038
- Oral chronic graft-versus-host disease: report from the International Consensus Conference on clinical practice in cGVHD.Clin Oral Investig. 2011; 15: 127-139
- National Institutes of Health consensus development Project on Criteria for clinical Trials in chronic graft-versus-host disease: V. The 2014 ancillary therapy and supportive care Working group report.Biol Blood Marrow Transplant. 2015; 21: 1167-1187
- Cancer and oral care of the cancer patient.in: Little J.W. Falace D.A. Miller C.S. Dental management of the medically compromised patient. 8th edition. Elsevier Mosby, St Louis (MO)2013: 459-492
- Oral complications of nonsurgical cancer therapies: diagnosis and treatment.in: Glick M. Burket’s oral medicine. 12th edition. People’s Medical Publishing House, Shelton (CT)2015: 201-218
Article info
Footnotes
Disclosures: S. Elad is the Medical Expert of the BUM5 study, sponsored by Falk Pharma, GmbH; Y. Zadik is a co-investigator in the BUM5 study, sponsored by Falk Pharma, GmbH; N. Yarom is a site Principal Investigator for the BRONJ study, sponsored by Micromedic Technologies Ltd, Israel.
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
